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the body reaches a stable drug level at each dose before the next increase Missing a dose by a day or two is less consequential than it would be with a short-acting drug, though consistent weekly dosing is still recommended for optimal results This half-life extension approach is well-established in the GLP-1 drug class

Weighing herself at midday, after eating and drinking, and fully clothed, she observed a reading of 76kg nearly half a stone (4kg) more than her usual morning weight

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Holly Wyatt, an adjoint associate professor in medicine at the University of Colorado Anschutz

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