Glial cell-derived neurotrophic factor (GDNF) effectively protects nigral dopaminergic neurons from 6-hydroxydopamine (6-OHDA) damage by promoting palmitoylation modification of neural cell adhesion molecules (NCAMs), which significantly enhances their localization in lipid raft microregions
Monitor cognition and brain health : If using GLP-1 agents, baseline cognitive testing (memory, executive function) and periodic follow-up may help document whether there is slowing of decline (though in routine practice, this is limited)
Rachele, Restores Chief Science Officer, adds
Gastrointestinal : Nausea, abdominal discomfort
metformin for women with PCOS A 2017 randomized controlled trial comparing metformin to a GLP-1 agonist found that obese women with PCOS who took the GLP-1 agonist lost an additional 2 kg (4.4 lbs), had more frequent menstrual cycles, and had a higher rate of achieving pregnancy (43.6% vs
Elevated GH levels are associated with several anti-aging benefits
