Rosenstock J, Frias J, Jastreboff AM et al (2023) Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA
Cell 182:32888429, 16061622.e23
Based on the different molecular structures and PK characteristics of the GLP-1 RAs and the presence of GLP-1 receptors on the sinoatrial node, differential effects on HR may be expected
Die Prparate gelten als Lifestyle-Medikamente, die in erster Linie einer Verbesserung der Lebensqualitt dienen
Cardiovascular Benefits Semaglutide also offers cardiovascular benefits, particularly for individuals with type 2 diabetes
The provider may increase it gradually based on the approved schedule, your response, and your side effects