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Similarly, animal experiments have shown that the expression of liver tissue FAS and ACC-a mRNA in rats in the Lira group was significantly higher than the control ratio [55]

Besides, we demonstrated the shared mechanistic connections between chronic ethanol exposure and AD: oxidative stress and neuroinflammation, proved that chronic ethanol exposure may accelerate AD pathology by increasing A aggregation in mice and causing oxidative stress and neuroinflammatory impairments

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N Engl J Med 2010;363:19381948

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